Wellspring Oncology

Cancer Case Study: CyberKnife® Robotic Radiosurgery

CyberKnife treatment resultsCyberKnife® Robotic Radiosurgery System Pulmonary Case Study
NSCLC Left Upper Lung


  1. 65-year-old female presenting with a 1.5 cm x 2.0cm pulmonary nodule in the left upper lobe
  2. Histology: Poorly differentiated non-small cell lung carcinoma with focal squamous features
  3. Stage: T1 N0 M0


  1. Cyber Knife Treatment resultsPatient refused surgery due to long-term recovery concerns
  2. Conventional radiation therapy would require large margins of normal tissue irradiation, increasing risks of treatment morbidities. Stereotactic radiosurgery with the CyberKnife® System was chosen given the ability to reduce dose to surrounding tissues, skin, muscle, and bone


  1. Coronal planning image showing the tumor, lung parenchyma and isodose curves
  2. 3D image of bony anatomy, segmented lung, and beam orientations


  1. Prescription dose of 48 Gy delivered to 71% isodose line in 3 fractions
  2. Treatment included 154 non-coplanar, non-isocentric beams per fraction


  • Three months after treatment with the CyberKnife® System, patient reported no signs or symptoms of local regional recurrence or treatment related toxicity
  •  Patient had a complete radiographic response at 15 weeks
  • Patient continues to be free of disease at 10 month follow-up by PET CT

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